Objective: This study aims to quantitatively and qualitatively investigate the trends in multiple myeloma research and evaluate research hotspots using bibliometric analysis.

Methods: We collected all relevant publications on multiple myeloma research from 2010 to 2019 in the Web of Science Core Collection. CiteSpace software and Online Analysis Platform of Bibliometrics were used to analyze the distribution of document types, annual number of articles published, countries, institutions, journals, authors and keywords.

Results: We analyzed 7404 papers about multiple myeloma published from 2010 to 2019 in the Web of Science Core Collection. The United States had the highest number of total publications (2906, 39.2%) in the past 10 years, which has an extremely important influence, followed by China and Italy. The analysis of international cooperation showed that the United States cooperates most frequently with other countries. Among all institutions, the largest number of publications was Mayo Clinic (775, 10.5%). Anderson KC, Moreau P and Goldsch-midt H were the authors with the most published papers, while Palumbo A, Moreau P and Anderson KC were the most cited authors. The top 10 most productive institutions were located mainly in the USA, and the top 10 authors originated mainly from the USA and other European countries. Blood, Leukemia & Lymphoma, and Leukemia were the three journals that published the most articles. The top 10 journals with the largest number of published papers are all from developed countries, and four of them are from the United States. Clinical trials, carfilzomib and immunotherapy have been the hotspots in recent years, and monoclonal antibody and biomarker were found to be frontiers in this field and may be the focus of research in the next few years.

Conclusions: We analyzed and summarized the global research on multiple myeloma in the past decade. This research provides a comprehensive analysis, including country and institution of origin, authors, journals and keywords, while revealing research hotspots and frontiers in multiple myeloma research.

No relevant conflicts of interest to declare.

Author notes

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Asterisk with author names denotes non-ASH members.

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